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понедельник, 9 апреля 2012 г.

Inhaled corticosteroids are used to treat patients with early stages of asthma exacerbation


Inhaled steroids are ordinarily indicated to cure persons with early asthma complications.
According to several latest studies, one may increase the standard quantity of inhaled steroids by 8 times, but positive effects will be not increased in such situation. Ejaz Yousef, an expert who has been involved in these studies, notices that if a doctor observes that medical position of a patient becomes worse, he/she may recommend applying oral steroids instead of increasing the quantity of inhaled corticosteroids. Enhancing the dose of inhaled corticosteroids is not without any undesirable response. This factor causes various adverse effects. For example, the hypothalamic-pituitary adrenal axis may be suppressed in such case.  
Usage of inhaled corticosteroids was considered to be alternative therapy to taking oral medications. It was in 1997. It was fixed to prescribe inhaled corticosteroids as alternatives of oral products which are utilizable for patients with asthma complications.
Then, certain researches have displayed that application of enhanced measures of inhaled steroids systematically doesn’t enhance positive effects.
Yousef and his colleagues have conducted a study which implicated almost 200 kids of 2-17 years. These kids were cured with inhaled corticosteroids during 3 months. They were chosen randomly for treatment for a period of 12 days. Any child that had asthma complications was given inhaled steroids. Then the results were evaluated by the doctors.
No any child who smoked, had symptoms of chronic asthma or lung pathology was involved in the study.
Patients had to let know about their adverse results via telephone within 72 hours.  So, it was reported about cough during nighttime, wheeze, shortness of breath and intolerance  when it comes to exercises. Every response was evaluated according to a score that was ranged from 0 to 4. 0 meant no any response; 4 meant the most enhanced severity level.
Only 4 kids out of 82 the kids that were given high dosages of inhaled corticosteroids had to use systemic corticosteroids. Two2 of them were given doubled quantities; others 2 were applying the dosage that was more enhanced by 8 times than a standard one.
According to the results of the study, effectiveness of the medicines, placebo effect, supervision of doctors and treatment of patients during early stages of asthma exacerbation were responsible for acquiring good results.
This as well as other studies demonstrate that not each story about steroids is linked with abuse and administration of them for performance-enhancing effects. Steroids are utilizable for numerous medical cases.

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